Polynucleotide Therapy
Prescribing clinician-led bio-stimulating therapy designed to support collagen production, improve skin firmness and target specific concerns including under-eye rejuvenation.
What are polynucleotides?
Polynucleotides (PN) are long chains of nucleotides — the building blocks of DNA — that act as powerful bio-stimulators when injected into the skin. They promote tissue regeneration by stimulating fibroblast activity, which in turn boosts the production of collagen and elastin.
Unlike fillers, which add volume, polynucleotides work by improving the quality and structure of the skin itself. The result is firmer, more hydrated, more resilient skin that looks naturally healthier.
Polynucleotide therapy has become one of the most sought-after regenerative treatments in aesthetic medicine, particularly for the delicate under-eye area where traditional fillers carry higher risk.
Pricing
Consultation
£30
Medical aesthetics consultation
Single Treatment
from £250
Course recommended for best results
A course of treatments is recommended for optimal results. Package pricing is available — ask during your consultation.
Key treatment areas
Under-eye rejuvenation
One of the most effective treatments for dark circles, hollowing and crepey skin under the eyes — an area where many other treatments are unsuitable.
Full face rejuvenation
Improving overall skin quality, firmness and hydration across the face for a refreshed, more youthful appearance.
Neck rejuvenation
Addressing skin laxity, fine lines and crepey texture on the neck — an area that often shows signs of ageing early.
Décolletage
Improving skin texture and firmness on the chest area, which is commonly affected by sun damage and ageing.
What to expect
Skin assessment
A detailed evaluation of your skin concerns, quality and goals. We discuss what polynucleotides can realistically achieve and whether they are the right option for you.
Treatment
Polynucleotides are injected using fine needles into the targeted area. The procedure typically takes 20–30 minutes and is well tolerated.
Recovery
Mild swelling or bruising may occur, particularly in the under-eye area. This typically resolves within a few days. There is no significant downtime.
Results
Improvements develop gradually over 2–4 weeks as the bio-stimulation takes effect. A course of 2–3 sessions is typically recommended for optimal results.
Polynucleotides vs PDRN — what's the difference?
Both polynucleotides and PDRN are skin-rejuvenating treatments that come from the same natural source. They both work by encouraging your skin to repair and renew itself — but they do it in slightly different ways.
PDRN
Think of PDRN as a “signal sender” — it triggers your skin cells to start repairing and producing more collagen. It's particularly good at calming inflammation and kick-starting the healing process.
Polynucleotides
Polynucleotides do the same signalling, but they also act like a “scaffold” — giving your skin extra structural support while it rebuilds. This makes them especially effective for areas that need both firmness and hydration, like under the eyes.
During your consultation, we'll recommend which option — or combination — is best suited to your skin and what you're hoping to achieve. There's no need to decide beforehand.
Healthier, firmer skin — from the inside out
Book a consultation to discuss whether polynucleotide therapy is right for your skin concerns.
Book a consultation